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Abstract Berberine, a bioactive isoquinoline alkaloid derived from medicinal plants such as Berberis and Coptis species, shows significant promise for managing obesity and associated metabolic disorders

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Semaglutide and liraglutide were grouped separately from other GLP-1RAs because, at the time of the study, they were the only two with a FDA-approved indication for chronic weight management (tirzepatide was not approved for this purpose until November 2023) [3, 4]