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The U.S. Food and Drug Administration (FDA) has issued a warning to Novo Nordisk over its alleged failure to report adverse side effects, including death, in patients who took its GLP-1 medications

Some patients experience mild constipation early in semaglutide treatment, which can indirectly reduce overall gut transit time and nutrient absorption efficiency

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So that's one thing that you can for sure see, and you can see a lot of things there with hints towards addiction