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Discover the potential benefits and important considerations of pairing GLP-1 medications with hormone therapy during menopause—your guide to making informed decisions for your health. https://bit.ly/3UaWg3n
Liraglutide, with a half-life of 11–15 h, produces daily peaks and troughs and is more amenable to time-of-day tailoring, whereas semaglutide (half-life ~165–168 h) and tirzepatide (half-life ~117 h) provide near-continuous receptor engagement across the 24 h cycle with once-weekly dosing [75,76]
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The benefits of these medications for glycaemic control and cardiovascular risk reduction generally outweigh the potential pancreatic risks in appropriately selected patients
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